Stamford-Bridge.com: All Time Replaced By Sub
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| Name | Appearances | |
| 1 | Willian | 140 |
| 2 | Joe Cole | 138 |
| 3 | Eden Hazard | 123 |
| 4 | Gianfranco Zola | 112 |
| 5 | Eiður Guðjohnsen | 98 |
| 6 | Didier Drogba | 96 |
| 7 | Pedro | 94 |
| 8 | Oscar | 91 |
| 9 | John Obi Mikel | 89 |
| 10 | Mateo Kovačić | 87 |
| 11 | Salomon Kalou | 79 |
| 12 | Florent Malouda | 73 |
| 13 | Frank Lampard | 66 |
| Juan Mata | 66 | |
| Mason Mount | 66 | |
| 16 | Damien Duff | 63 |
| 17 | Graeme Le Saux | 62 |
| 18 | Jorginho | 57 |
| 19 | Ramires | 56 |
| 20 | Dan Petrescu | 55 |
| 21 | Nicolas Anelka | 54 |
| 22 | Jimmy Floyd Hasselbaink | 53 |
| 23 | Jesper Grønkjær | 50 |
| Kai Havertz | 50 | |
| 25 | Victor Moses | 49 |
| Christian Pulisic | 49 | |
| 27 | Arjen Robben | 47 |
| 28 | John Bumstead | 46 |
| Cesc Fàbregas | 46 | |
| 30 | César Azpilicueta | 45 |
| Hakim Ziyech | 45 | |
| 32 | N'Golo Kanté | 43 |
| Olivier Giroud | 43 | |
| Raheem Sterling | 43 | |
| 35 | Shaun Wright-Phillips | 42 |
| Diego Costa | 42 | |
| 37 | Callum Hudson-Odoi | 41 |
| 38 | Michael Ballack | 39 |
| Fernando Torres | 39 | |
| Ruben Loftus-Cheek | 39 | |
| 41 | Jody Morris | 38 |
| Tore André Flo | 38 | |
| Andriy Shevchenko | 38 | |
| 44 | Marcos Alonso | 35 |
| Ross Barkley | 35 | |
| 46 | Michael Essien | 34 |
| Timo Werner | 34 | |
| 48 | Gus Poyet | 33 |
| 49 | Hernan Crespo | 32 |
| Ashley Cole | 32 | |
| 51 | John Terry | 31 |
| Claude Makélélé | 31 | |
| 53 | John Spencer | 30 |
| Roberto Di Matteo | 30 | |
| Mykhailo Mudryk | 30 | |
| 56 | Craig Burley | 29 |
| José Bosingwa | 29 | |
| Andreas Christensen | 29 | |
| Tammy Abraham | 29 | |
| Noni Madueke | 29 | |
| 61 | André Schürrle | 28 |
| Álvaro Morata | 28 | |
| 63 | Celestine Babayaro | 27 |
| Mario Stanić | 27 | |
| 65 | Ben Chilwell | 26 |
| 66 | Gordon Durie | 25 |
| Daniel Sturridge | 25 | |
| Nicolas Jackson | 25 | |
| 69 | Peter Osgood | 24 |
| Steve Clarke | 24 | |
| Boudewijn Zenden | 24 | |
| Paulo Ferreira | 24 | |
| Enzo Fernández | 24 | |
| 74 | Micky Hazard | 23 |
| Dennis Wise | 23 | |
| Frank Leboeuf | 23 | |
| Albert Ferrer | 23 | |
| 78 | David Rocastle | 22 |
| Emmanuel Petit | 22 | |
| Geremi | 22 | |
| Branislav Ivanović | 22 | |
| 82 | Graham Stuart | 21 |
| Marc Cucurella | 21 | |
| 84 | Peter Rhoades-Brown | 20 |
| Nigel Spackman | 20 | |
| Samuel Eto'o | 20 | |
| Nemanja Matić | 20 | |
| Cole Palmer | 20 | |
| 89 | Kerry Dixon | 19 |
| Conor Gallagher | 19 | |
| 91 | Mark Hughes | 18 |
| Mario Melchiot | 18 | |
| Adrian Mutu | 18 | |
| Reece James | 18 | |
| 95 | Andy Myers | 17 |
| Gavin Peacock | 17 | |
| Didier Deschamps | 17 | |
| Ricardo Carvalho | 17 | |
| Deco | 17 | |
| 100 | Charlie Cooke | 16 |
| Kevin Wilson | 16 | |
| Frank Sinclair | 16 | |
| Eddie Newton | 16 | |
| Marcel Desailly | 16 | |
| David Luiz | 16 | |
| 106 | Clive Walker | 15 |
| Pat Nevin | 15 | |
| Kevin McAllister | 15 | |
| Gianluca Vialli | 15 | |
| Tiago Mendes | 15 | |
| Raul Meireles | 15 | |
| Malo Gusto | 15 | |
| 113 | Bobby Tambling | 14 |
| Ian Hutchinson | 14 | |
| Ian Britton | 14 | |
| Gareth Hall | 14 | |
| Neil Shipperley | 14 | |
| Scott Minto | 14 | |
| Yuri Zhirkov | 14 | |
| Romelu Lukaku | 14 | |
| 121 | Tommy Baldwin | 13 |
| David Speedie | 13 | |
| Robert Fleck | 13 | |
| Glen Johnson | 13 | |
| Loïc Rémy | 13 | |
| Michy Batshuayi | 13 | |
| Davide Zappacosta | 13 | |
| Thiago Silva | 13 | |
| Moisés Caicedo | 13 | |
| 130 | Bill Garner | 12 |
| Colin Pates | 12 | |
| Paul Canoville | 12 | |
| Mal Donaghy | 12 | |
| Mark Stein | 12 | |
| Chris Sutton | 12 | |
| Scott Parker | 12 | |
| Juliano Belletti | 12 | |
| Pierre-Emerick Aubameyang | 12 | |
| 139 | Peter Houseman | 11 |
| Peter Nicholas | 11 | |
| Erland Johnsen | 11 | |
| Jon Harley | 11 | |
| Sam Dalla Bona | 11 | |
| Alexey Smertin | 11 | |
| Demba Ba | 11 | |
| Armando Broja | 11 | |
| 147 | Micky Droy | 10 |
| Garry Stanley | 10 | |
| Colin Lee | 10 | |
| David Lee | 10 | |
| David Hopkin | 10 | |
| Pierluigi Casiraghi | 10 | |
| Bjarne Goldbæk | 10 | |
| William Gallas | 10 | |
| Enrique de Lucas | 10 | |
| Wayne Bridge | 10 | |
| Kenedy | 10 | |
| Trevoh Chalobah | 10 | |
| João Félix | 10 | |
| 160 | Keith Jones | 9 |
| Alan Dickens | 9 | |
| Mikael Forssell | 9 | |
| Mateja Kežman | 9 | |
| Asier Del Horno | 9 | |
| Lassana Diarra | 9 | |
| Oriol Romeu | 9 | |
| Kurt Zouma | 9 | |
| Gonzalo Higuain | 9 | |
| 169 | John Hollins | 8 |
| Ron Harris | 8 | |
| John Boyle | 8 | |
| Eddie McCreadie | 8 | |
| Gary Locke | 8 | |
| Clive Wilson | 8 | |
| Ken Monkou | 8 | |
| Damian Matthew | 8 | |
| Ruud Gullit | 8 | |
| Mark Nicholls | 8 | |
| Paul Hughes | 8 | |
| Gabriele Ambrosetti | 8 | |
| Slaviša Jokanović | 8 | |
| Petr Cech | 8 | |
| Mohamed Salah | 8 | |
| Levi Colwill | 8 | |
| 185 | John Dempsey | 7 |
| Steve Finnieston | 7 | |
| Graham Wilkins | 7 | |
| Trevor Aylott | 7 | |
| Kevin Hales | 7 | |
| Paul Furlong | 7 | |
| Khalid Boulahrouz | 7 | |
| Claudio Pizarro | 7 | |
| Alex | 7 | |
| Ryan Bertrand | 7 | |
| Gary Cahill | 7 | |
| Wesley Fofana | 7 | |
| 197 | Chris Garland | 6 |
| Steve Kember | 6 | |
| Mike Fillery | 6 | |
| Micky Nutton | 6 | |
| Alan Mayes | 6 | |
| Mickey Thomas | 6 | |
| Joe McLaughlin | 6 | |
| Darren Wood | 6 | |
| Tom Boyd | 6 | |
| Tony Cascarino | 6 | |
| Darren Barnard | 6 | |
| Andy Dow | 6 | |
| Steve Sidwell | 6 | |
| Yossi Benayoun | 6 | |
| Antonio Rüdiger | 6 | |
| Lewis Hall | 6 | |
| Denis Zakaria | 6 | |
| Axel Disasi | 6 | |
| Christopher Nkunku | 6 | |
| 216 | Marvin Hinton | 5 |
| Alan Birchenall | 5 | |
| Alan Hudson | 5 | |
| Roy Wegerle | 5 | |
| Tony Dorigo | 5 | |
| Joe Allon | 5 | |
| Paul Elliott | 5 | |
| Vinnie Jones | 5 | |
| Mick Harford | 5 | |
| Michael Duberry | 5 | |
| Jes Høgh | 5 | |
| Gaël Kakuta | 5 | |
| Josh McEachran | 5 | |
| Marko Marin | 5 | |
| Tiémoué Bakayoko | 5 | |
| Danny Drinkwater | 5 | |
| Billy Gilmour | 5 | |
| Saúl | 5 | |
| Alfie Gilchrist | 5 | |
| Pedro Neto | 5 | |
| 236 | David Webb | 4 |
| Ray Wilkins | 4 | |
| Tommy Langley | 4 | |
| Duncan McKenzie | 4 | |
| Dennis Rofe | 4 | |
| Graham Roberts | 4 | |
| Glenn Hoddle | 4 | |
| Anthony Barness | 4 | |
| Bernard Lambourde | 4 | |
| Brian Laudrup | 4 | |
| George Weah | 4 | |
| Robert Huth | 4 | |
| Scott Sinclair | 4 | |
| Kevin de Bruyne | 4 | |
| Juan Cuadrado | 4 | |
| Baba Rahman | 4 | |
| Bertrand Traoré | 4 | |
| Emerson | 4 | |
| Kalidou Koulibaly | 4 | |
| Carney Chukwuemeka | 4 | |
| Benoît Badiashile | 4 | |
| 257 | Paddy Mulligan | 3 |
| John Sparrow | 3 | |
| Brian Bason | 3 | |
| Steve Wicks | 3 | |
| David Stride | 3 | |
| Gary Johnson | 3 | |
| Phil Driver | 3 | |
| Bryan Robson | 3 | |
| Joey Jones | 3 | |
| Gordon Davies | 3 | |
| Keith Dublin | 3 | |
| John McNaught | 3 | |
| Andy Townsend | 3 | |
| Dmitri Kharine | 3 | |
| Jakob Kjeldbjerg | 3 | |
| Danny Granville | 3 | |
| Ed de Goey | 3 | |
| Carlton Cole | 3 | |
| Juan Sebastian Veron | 3 | |
| Carlo Cudicini | 3 | |
| Jiří Jarošík | 3 | |
| Filipe Luís | 3 | |
| Édouard Mendy | 3 | |
| Jadon Sancho | 3 | |
| 281 | Tony Hateley | 2 |
| Allan Harris | 2 | |
| Keith Weller | 2 | |
| Peter Bonetti | 2 | |
| Kenny Swain | 2 | |
| Teddy Maybank | 2 | |
| Ray Lewington | 2 | |
| Lee Frost | 2 | |
| Eamonn Bannon | 2 | |
| Gary Chivers | 2 | |
| Tony McAndrew | 2 | |
| Dale Jasper | 2 | |
| Jerry Murphy | 2 | |
| Doug Rougvie | 2 | |
| Eddie Niedzwiecki | 2 | |
| Colin West | 2 | |
| John Coady | 2 | |
| Dave Mitchell | 2 | |
| Jason Cundy | 2 | |
| Terry Phelan | 2 | |
| Christian Panucci | 2 | |
| Maniche | 2 | |
| Michael Mancienne | 2 | |
| Sam Hutchinson | 2 | |
| Nathaniel Chalobah | 2 | |
| Ola Aina | 2 | |
| Ethan Ampadu | 2 | |
| Fikayo Tomori | 2 | |
| Malang Sarr | 2 | |
| Lesley Ugochukwu | 2 | |
| Ian Maatsen | 2 | |
| Marc Guiu | 2 | |
| 313 | George Graham | 1 |
| Bert Murray | 1 | |
| Terry Venables | 1 | |
| Barry Bridges | 1 | |
| Allan Young | 1 | |
| Joe Fascione | 1 | |
| Jim Thomson | 1 | |
| Colin Waldron | 1 | |
| Barry Lloyd | 1 | |
| Derek Smethurst | 1 | |
| Tommy Ord | 1 | |
| Petar Borota | 1 | |
| Jim Docherty | 1 | |
| Chris Hutchings | 1 | |
| Timmy Elmes | 1 | |
| Terry Howard | 1 | |
| John Millar | 1 | |
| Robert Isaac | 1 | |
| Clive Allen | 1 | |
| Neil Clement | 1 | |
| Kevin Hitchcock | 1 | |
| Paul Parker | 1 | |
| Frode Grodås | 1 | |
| Winston Bogarde | 1 | |
| Mark Bosnich | 1 | |
| Alexis Nicolas | 1 | |
| Tal Ben Haim | 1 | |
| Ricardo Quaresma | 1 | |
| Henrique Hilário | 1 | |
| Patrick van Aanholt | 1 | |
| Lucas Piazon | 1 | |
| Marco van Ginkel | 1 | |
| Thibaut Courtois | 1 | |
| Nathan Aké | 1 | |
| Matt Miazga | 1 | |
| Alexandre Pato | 1 | |
| Radamel Falcao | 1 | |
| Jérémie Boga | 1 | |
| Charly Musonda | 1 | |
| Tino Anjorin | 1 | |
| Xavier Simons | 1 | |
| Harvey Vale | 1 | |
| Jude Soonsup-Bell | 1 | |
| Kepa Arrizabalaga | 1 | |
| David Fofana | 1 | |
| Robert Sánchez | 1 | |
| Diego Moreira | 1 | |
| Mason Burstow | 1 | |
| Roméo Lavia | 1 |
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